Factors influencing the decline in lung density in a Danish lung cancer screening cohort

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Factors influencing the decline in lung density in a Danish lung cancer screening cohort.

Lung cancer screening trials provide an opportunity to study the natural history of emphysema by using computed tomography (CT) lung density as a surrogate parameter. In the Danish Lung Cancer Screening Trial, 2,052 participants were included. At screening rounds, smoking habits were recorded and spirometry was performed. CT lung density was measured as the volume-adjusted 15th percentile densi...

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Factors influencing decline in lung density in a Danish lung cancer screening cohort

Department of Respiratory Medicine, Gentofte Hospital, Denmark Department of Computer Science (DIKU), University of Copenhagen, Denmark Department of Biostatistics, University of Copenhagen, Denmark Departments of Medical Informatics and Radiology, Erasmus MC Rotterdam, The Netherlands Department of Thoracic Surgery RT, Rigshospitalet, University of Copenhagen, Denmark . Published on March 9, 2...

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Background: The dosimetric parameters required in lung cancer radiation therapy are taken from a homogeneous water phantom; however, during treatment, the expected results are being affected because of its inhomogeneity. Therefore, it becomes necessary to quantify these deviations.Objective: The present study has been undertaken to find out inter- and intra- lung density variations and its dosi...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2012

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.00207911